Nocisens® INTENSE


1541 in stock

  • Concentrated neurodermatological cream indicated to improve uncomfortable sensations in areas prone to irritation or recurrent outbreaks.
  • We recommend applying it twice daily until the cutaneous balance is restored.
  • Can be combined with Nocisens® OIL for maintenance. 

30 mL | Dermatologically tested | Hypoallergenic

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If you have sensitive and atopic-prone skin and present areas prone to irritation or frequent outbreaks, which are aggravated by stress, pollution, or weather changes.

Nocisens® INTENSE can help you mitigate these uncomfortable sensations, prevent their reappearance, and moisturize and balance your skin.

The Nocisens® line has been carefully formulated to respect sensitive skin. Its innovative composition contains:

  • Hydroxymethoxyiodobenzyl glycolamide pelargonate, a novel neurodermatological ingredient that acts at the level of the sensory receptors of the epidermis, relieving uncomfortable sensations produced by dryness and dermal sensitivity. In addition, its continued use restores the epidermal barrier by preventing water loss and strengthening the skin’s natural defense. It results from several years of scientific research1-3 by the Sensory Neurobiology group of the Institute for Research, Development, and Innovation in Health Biotechnology of the Universidad Miguel Hernández de Elche.
  • A combination of fatty acids with a powerful moisturizing action that provides a smooth texture and favors the action of the cream in the deepest layers of the epidermis.
  • Antioxidant molecules, such as tocopherol, prevent the main components of the skin from oxidation and deterioration due to daily aggressions.



  1. Serafini M., et al., Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders. Journal of Medicinal Chemistry. 61 (2018) 4436-4455.
  2. López- González et al. Improving a Natural Compound: Design of Innovative neurocosmeceuticals for Sensitive Skin. IFSCC. Vol 23 (2018) 1; 37-44.
  3. Fernández Carvajal A et al. Moduladores del termorreceptor TRPV1 desactivables metabólicamente en la farmacología del prurito. Rev. Soc. Esp. Farmacol. Vol 18 (2020) 3: (en prensa).


CN 204614.6

Nocisens® INTENSE has twice the active ingredient concentration of Nocisens® OIL, so its action is more powerful.

We recommend using Nocisens® INTENSE or the most sensitive areas or areas with outbreaks and Nocisens® OIL for daily skin maintenance.

Nocisens® INTENSE is indicated for children from 3 years of age.

Children under three years of age can use Nocisens® BABY, which is specially formulated for their skin.

Yes, we recommend using Nocisens® INTENSE twice daily.

It is a concentrated and moisturizing cream that can help you strengthen dry skin and combat discomfort.

You can use Nocisens® INTENSE simultaneously with other topical products or drugs, such as corticosteroids or antibiotics.

We recommend applying Nocisens® INTENSE and waiting until it has been absorbed before applying another product.

You can apply Nocisens® INTENSE to dry or sensitive areas all over the body, including the face.

Avoid contact with mucous membranes or open wounds. You can use a cotton pad to remove excess product from delicate areas such as eyelids.

Nocisens® INTENSE is very effective in combating dryness and itching. If you suffer from either of these conditions, Nocisens® INTENSE can significantly help.

However, Nocisens® INTENSE has a concentrated and moisturizing texture that may not be well tolerated by oily skin.

Studies carried out by independent companies have shown that Nocisens® products are well tolerated by all skin types, including sensitive skin in children:1,2

  • 100% of users stated that their skin felt softer and calmer after using Nocisens®.
  • 95% of users think that Nocisens® moisturizes and nourishes the skin.
  • 85% of users found their skin more supple and elastic after using Nocisens®.
  • 85% of users felt comfort after using Nocisens®.



  1. Studies carried out by independent companies to measure the efficacy and tolerance of Nocisens® objectively in volunteers. They measured skin capacitance with the Corneometer® and transepidermal water loss with the Tewameter®. Both measurements were carried out on day 0 (before using the product) and after 28 days of use under professional control.
  2. An independent company conducted the tests on a panel of 22 male and female subjects between 19 and 65

All our creams include innovative neurodermatological ingredients. These active ingredients act on the skin’s neurosensory system, which causes uncomfortable sensations such as itching, stinging, or pain.

These actives are combined in Nocisens® with other highly moisturizing ingredients that help to mitigate dryness and restore the cutaneous balance. Nocisens® line acts on the skin moisturizing, balancing, and relieving sensory discomfort.


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