Neurodermatology and neurocosmetics for skin care

More than 50% of the population in Western countries suffers from some type of skin sensitivity caused mainly by chronic diseases such as atopic dermatitis or hyperhidrosis, treatments such as chemotherapy or radiotherapy, or environmental conditions such as pollution.

This sensitivity manifests as itching, stinging, irritation, or tingling that affects the quality of life of those suffering from it.

In the constant search for innovations, neurodermatology and neurocosmetics emerge as allies in sensitive skin care. You may have heard of these terms, but do you know what they are? What is the difference between them?

Keep reading to find out!

The neurosensory system at the center of skincare

Before discussing neurodermatology and neurocosmetics, we will discuss the neurosensory system.

Our skin and our brain are connected through the neurosensory system. This fundamental part of the nervous system is responsible for detecting, transmitting, and processing information from the environment, such as light, touch, temperature, and pressure.

In the case of the skin, this system allows us to perceive stimuli through its receptors and trigger a sensory response that protects us and or adapts to its presence (pleasure, pain, itching, burning, stinging, heat, and flushing).

External stimuli, such as increased temperature, activate the skin’s sensory receptors, which send a signal through the sensory neurons (1). This signal travels through the spinal cord (2) to the central nervous system (CNS) (3). The central nervous system sends a signal back to respond to this stimulus.

These receptors on the surface of our skin can be damaged or hyperactivated due to stimuli such as inflammation present in some diseases or aggressive agents, such as those found in chemotherapy. This damage or hyperactivation leads to disabling sensory discomfort, such as itching or tingling.

Although the neurosensory system is the main component that triggers the uncomfortable sensations of sensitive skin, current strategies for sensitive skin care do not address it. Neurodermatology and neurocosmetics put the neurosensory system at the center of skin care.

Differences between neurodermatology and neuroscometics

Neurodermatology is the branch of dermatology that allows us to understand how our brain and nervous system affect skin health. It studies the mechanisms of action of the skin’s nervous system and the imbalances that occur in it. Neurodermatology is the key to discovering molecules that act on overactive skin receptors, rebalancing their activity and helping to calm uncomfortable sensations.Neurocosmetics applies this understanding to develop cosmetic products that use this knowledge to care for the skin, improve its appearance, and help soothe the discomfort of sensitive skin, such as itching, burning, or stinging, by acting on the neurosensory system

Prospera Biotech: pioneers in neurodermatology and neuroscometics

At Prospera Biotech, we are pioneers in neurodermatology and neurocosmetics. We develop neurocosmetic products for sensitive skin, addressing all its components. We have been researching for over 25 years through the Institute in Health Biotechnology of the Miguel Hernández University (UMH) of Elche, Spain.

Our products put the neurosensory system at the center of skincare to improve the skin’s appearance and help reduce discomfort. They contain ingredients combined with other beneficial active ingredients to target specifically:

  • Sensitive and atopic-prone skin. The Nocisens® line is indicated for the daily care of sensitive and atopic-prone skin, reducing typical discomforts such as itching and burning. It also contains avocado oil and oat extract that help to moisturize and nourish the skin. 
  • Excessive sweating. Ecrisens® helps control excessive sweating without affecting the body’s thermoregulatory needs by making the sweat glands less sensitive to heat and decreasing their activation.
  • Itching in the external intimate area. Vulvisens® combines prebiotic ingredients that help restore and strengthen the natural microbiota, antioxidants and reepithelializing agents that help regenerate areas damaged by previous infections, and neurocosmetic active ingredients that restore the sensitive balance and help soothe itching.
  • Discomfort derived from chemotherapy treatment. Oncapsisens® works by helping to reduce the typical discomfort of skin undergoing chemotherapy treatment. It strengthens the skin’s balance by moisturizing and helping to soothe uncomfortable sensations.

We continue our research to develop solutions for other types of sensitive skin. R&D is an essential part of our DNA.

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  • Fernández Carvajal A, Devesa I, Fernández Ballester G, Ferrer Montiel A. Moduladores del termorreceptor TRPV1 desactivables metabólicamente en la farmacología del prurito. Rev Soc Esp Farmacol. 2020;18(3):162-72.
  • Gadhvi M, Moore MJ, Waseem M. Physiology, Sensory System. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. [Actualizado 6 May 2023]; [citado 30 Abril 2024] Disponible en:
  • Wohlrab J, Bechara FG, Schick C, Naumann M. Hyperhidrosis: A Central Nervous Dysfunction of Sweat Secretion. Dermatol Ther (Heidelb). 2023;13(2):453-463.


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